Hi there!
Some of my users are first-time-blog-users :-) I don't want them to quit just because of the WP-Admin-menu.
What I'm looking for is a way to simplify the menu as much as possible - they should be able to write, edit posts and pages and manage their cathegories. No need for them to change other settings (e.g. options-general.php, plugins.php).
I think not only my users would like to concentrate on writing and not searching menus...