I am using this profile picture plugin as an mu-plugin. It adds a picture upload form on the profile page for each user and works great, except for a small problem that manifests in IE. Because the form in profile.php does not have an enctype of multipart/form-data, IE does not recognize the data portion of the post and the pictures are not uploaded to the server. Firefox seems to recognize it regardless of the missing enctype parameter.
Obviously, this is a change I can make on my own but I wonder if it might be wise to change the profile.php in svn for future releases so similar plugins that use <input type=file> on the profile page don't encounter the same issue.