WordPress MU

There's any guide for easy creation of themes?
Im not a designer and unfortunelly my designers are too lazy.

There's plenty of documentation out there: http://www.google.com/search?q=wordpress+how+to+create+themes

WordPress Codex: Theme Development
http://codex.wordpress.org/Theme_Development

And playing around with the classic theme might be a good start as has all the basic things you need.

Also check the regular WP codex.